Imaging
Imaging facilities are available through the Centre for Advanced Imaging (CAI), Herston Imaging Research Facility (HIRF) and Centre for Microscopy and Microanalysis (CMM).
Equipment includes whole body scanners, NMR spectrometers and animal imaging. Mass spectrometry imaging is also available.
Services
Comprehensive range of magnetic resonance imaging (MRI) and molecular structure identification, including whole body scanners, several high-resolution NMR spectrometers, solid state and EPR instruments and microimaging and animal imaging systems.
Equipment
Human Imaging
- 3T MRI scanner
- 7T MRI scanner
- Biograph Horizon PET/CT
Molecular Imaging
- ClinScan MR/PET
- Inveon PET/CT
- Biograph Horizon PET/CT
- IVIS Lumina X5 high-throughput optical imaging system
- iThera MSOT inVision 256-TF
Mass Spectrometry Imaging
- Bruker Autoflex MALDI-TOF/TOF MSI facility
Pre-clinical Animal Imaging
- 9.4T MRI preclinical
- Avance 16.4T preclinical - MR Microimaging
- Clinscan MR/PET
- Inveon PET/CT
- Bruker in vivo MS FX Pro optical imaging\
Radiochemistry Facility and Cyclotron
- IBA 18/18MeV cyclotron
EPR Spectroscopy and Imaging
- Bruker Elexsys E500 CW
- Bruker Elexsys E580 Pulsed Q-, X-band
- Bruker Elexsys E540 (X-, L-band) Imaging Scanner
Nuclear Magnetic Resonance (NMR) and NMR-based Metabolomics
- Avance 500 MHz NMR
- Avance 700 MHz NMR
- Avance 900 MHz NMR
- Solid State 300 MHz NMR
Physics support
Image Analysis and Methodology Development
Contact
Centre for Advanced Imaging (CAI)
Phone: 07 3365 4100
Email: enquiries@cai.uq.edu.au
Location: CAI Building 57, St Lucia campus
Services
The Herston Imaging Research Facility (HIRF) provides advanced imaging for clinical research. With its cutting-edge scanning technology, HIRF has the potential to revolutionise patient care, and is a perfect site for clinical trial work. The facility is an alliance between three leading university, research and healthcare institutions:
- The University of Queensland
- Queensland University of Technology
- Royal Brisbane and Women’s Hospital (through the Metro North Hospital and Health Service).
Equipment
- Siemens 3T Magnetom scanner PRISMA MRI
- Siemens Biograph ,CT Flow PET/CT
- Siemens 3T Biograph mMR PET/MRI
- Siemens Acuson Ultrasound S3000
VECTRA WB360 system for surface imaging - Hyperfine 0.5mT Swoop Portable MR System
- Protocol support, trained radiographers and nuclear medicine scientists.
Contact
Operations Manager
Website: Herston Imaging Research Facility
Phone: 07 3646 5820
Email: HIRFAdministration@health.qld.gov.au
Location: Level 3, UQCCR Building, Royal Brisbane and Women’s Hospital, Herston Precinct
Services
Mass Spectrometry Imaging produces the spatial distribution of various analyte classes present in tissue samples mounted on microscope slides. By bringing MSI together with other imaging modalities such as microscopy and MRI, a more holistic picture of biomolecular imaging can be achieved.
Within the facility we have a number of MALDI-TOF/TOF systems, and an atmospheric pressure MALDI which can be coupled to a QqTOF. We also have a JEOL MALDI Spiral-TOF, capable of higher mass resolving power (75,000). Another addition is a Bruker TIMS TOF Flex with MALDI-2, an instrument capable of both MALDI and Electrospray, making it a very useful instrument for Mass Spectrometry Imaging and companion LC-MS analysis.
We have installed a Waters MRT, which is DESI and MALDI enabled, and offers mass resolving power in excess of 200k, making it a very powerful instrument for MS Imaging and LC-MS. The broad range of instruments allow us to perform Mass Spectrometry Imaging for a diverse range of analytes.
In addition to mass spectrometers, we have a suite of supporting equipment including HPLC-spotting robots, and matrix deposition devices (both spray and vacuum sublimation based). A range of supporting software is also available, most of which can be accessed remotely.
Equipment
- Bruker Autoflex Speed (MALDI-TOF/TOF)
- Bruker Ultraflextreme (MALDI-TOF/TOF)
- Bruker MicroTOF Q II (QqTOF)
- Bruker TIMS TOF Flex with MALDI-2 (MALDI and ESI QqTOF with ion mobility)
- Waters MRT (MALDI and DESI)
- JEOL Spiral TOF (MALDI-TOF/TOF)
- Dionex HPLC with Proteineer spotting robot
- Dionex HPLC with Thermo QqQ MS
- Masstech AP-MALDI source
- Shimadzu IMlayer
- Thermo nanoHPLC with Proteineer Spotting Robot
- Thermo HPLC with Thermo QqQ MS
- Vacuum Sublimation Device
- Bruker Imageprep
- Sunchrom Matrix Sprayer
- Sunchrom Digester
- Basic histology including microtome for MSI sample prep
- Software available includes Mascot, SCILs Lab, Flex Imaging, ClinProt Tools, PEAKS Studio X, Metaboscape
Contact
Dr Brett Hamilton
Centre for Microscopy and Microanalysis - Novel Imaging
Phone: 0406 609 223
Email: b.hamilton@uq.edu.au or cmm@uq.edu.au
Location: Level 1, Hawken Building #50, St Lucia campus
Services
The Preclinical Imaging Unit supports translational and basic research programs by providing users access to a variety of high-end in vivo and ex vivo imaging instruments. Located within the TRI's Biological Resources Facility (BRF), a specific pathogen-free PC2 facility, researchers can utilise multiple imaging modalities in a single longitudinal study. High-resolution imaging of clinical samples or other materials is also possible on some equipment.
Equipment
The following equipment is available to all users as part of the 'Core Facilities at TRI':
- Bruker Molecubes X- and β-Cubes (PET/CT)
- Revvity IVIS Spectrum 2 (optical)
- Xstrahl Small Animal Radiation Research Platform (SARRP) (image-guided radiotherapy)
- Bruker Skyscan 1272 (ultra-high resolution microCT)
- Bruker Minispec LF50H (NMR for body composition analysis)
- Faxitron UltraFocus 100 (high-resolution X-ray)
- Visualsonics Vevo 2100 (ultrasound)
- Revvity Wizard 2480 (gamma counter)
- Targeted radionuclide therapies
- Suite of analysis computers and software
Contact
Translational Research Institute (TRI)
Website: TRI Preclinical Imaging Facility
Email: preclinicalcore@tri.edu.au
Location: Level 1, TRI Building (Building 48), Princess Alexandra Hospital campus